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天然产物对酒精性肝损伤的保护作用研究进展. (2025). 环球医学研究, 2(3), 9-20. https://doi.org/10.62836/medicine.v2i3.837
Copyright (c) 2025 崔新妍, 娄在祥, 段文杰, 段光志
This work is licensed under a Creative Commons Attribution 4.0 International License.
天然产物对酒精性肝损伤的保护作用研究进展
崔新妍1，娄在祥1*，段文杰2，段光志2
1. 江南大学食品学院，江苏无锡
2. 湖北仙之灵食品有限公司，湖北荆门
摘要：酒精性肝损伤是指由于长期或短期内大量饮酒引起的肝组织病变，逐渐会发展为脂肪肝、酒精性肝炎、纤维化、肝硬化和肝癌。近年来，天然产物因其靶点多、毒性低且副作用少的优点而受到越来越多的关注，一些天然产物及其活性成分被证明对酒精性肝损伤具有显著的保护作用。本文综述了酒精性肝损伤的主要发病机制，包括乙醇代谢、氧化应激、炎症反应、脂质代谢异常和肠道菌群失调等方面， 以及天然产物对酒精性肝损伤的防护作用和机制，以期为天然产物的进一步开发和利用提供参考。
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